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ISBN:0306418045
Author: Ulrich Huebscher
ISBN13: 978-0306418044
Title: Proteins Involved in DNA Replication (Advances in Experimental Medicine & Biology)
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ePUB size: 1819 kb
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Language: English
Category: Biological Sciences
Publisher: Springer; 1 edition (November 1, 1984)
Pages: 571

Proteins Involved in DNA Replication (Advances in Experimental Medicine & Biology) by Ulrich Huebscher



Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 179). This book collects the Proceedings of a workshop sponsored by the European Molecular Biology Organization (EMBO) entitled "Pro­ teins Involved in DNA Replication" which was held September 19 to 23,1983 at Vitznau, near Lucerne, in Switzerland.

Series: Advances in Experimental Medicine and Biology 179. File: PDF, 2. 7 M. This book collects the Proceedings of a workshop sponsored by the European Molecular Biology Organization (EMBO) entitled "Proteins Involved in DNA Replication" which was held September 19 to 23,1983 at Vitznau, near Lucerne, in Switzerland.

Proteins Involved in DNA Replication pp 45-54 Cite as. Proteins and Nucleotide Sequences Involved in DNA Replication of Filamentous Bacteriophage. Authors and affiliations. Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 179). Filamentous bacteriophages (fd, M13, f1) contain single-stranded circular DNA of about 6400 bases (1). They penetrate the host cell via pili induced by the F-episome of an Escherichia coli cell. During the penetration process their single-stranded genome is converted into double-stranded DNA which is the main viral component in the first minutes after infection. Later in the life cycle, viral single strands are formed and complexed with gene 5 protein

Advances in experimental medicine and biology ; v. 179. General Note: "Proceedings of a workshop on proteins involved in DNA replication sponsored by the European Molecular Biology Organization (EMBO) and held September 19-23, 1983 at Vitznau, Switzerland. Bibliography, etc. Note: Includes bibliographies and index. Personal Name: Hübscher, Ulrich.

The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the field.

Series: Advances in Experimental Medicine and Biology (Book 973). Hardcover: 304 pages. ISBN-13: 978-1461450368. Product Dimensions: . x . inches. Shipping Weight: . pounds (View shipping rates and policies).

Book · January 2012 with 5 Reads. Mitochondrial dysfunction and mutations in mitochondrial DNA have been implicated in a wide variety of human diseases, including cancer. In recent years, considerable advances in genomic, proteomic and bioinformatic technologies have made it possible the analysis of mitochondrial proteome, leading to the identification of over 1,000 proteins which have been assigned unambiguously to mitochondria. Defining the mitochondrial proteome is a fundamental step for fully understanding the organelle functions as well as mechanisms underlying mitochondrial pathology.

These epigenetic differences include DNA methylation at CpG dinucleotides, as well as modifications on the histones associated with the locus. In the simplest possible cases, the promoter region of the imprinted gene is methylated during oogenesis, but not spermatogenesis (or vice versa). This methylation (and its accompanying histone modifications) results in inactivation of the modified allele. Of course, most imprinted genes do not fall into this simplest case. Rather, the book covers on some of the more recent advances, with the goal of drawing attention to some of the emerging subtleties and complexities associated with imprinted genes.

This book collects the Proceedings of a workshop sponsored by the European Molecular Biology Organization (EMBO) entitled "Pro­ teins Involved in DNA Replication" which was held September 19 to 23,1983 at Vitznau, near Lucerne, in Switzerland. The aim of this workshop was to review and discuss the status of our knowledge on the intricate array of enzymes and proteins that allow the replication of the DNA. Since the first discovery of a DNA polymerase in Escherichia coli by Arthur Kornberg twenty eight years ago, a great number of enzymes and other proteins were des­ cribed that are essential for this process: different DNA poly­ merases, DNA primases, DNA dependent ATPases, helicases, DNA liga­ ses, DNA topoisomerases, exo- and endonucleases, DNA binding pro­ teins and others. They are required for the initiation of a round of synthesis at each replication origin, for the progress of the growing fork, for the disentanglement of the replication product, or for assuring the fidelity of the replication process. The number, variety and ways in which these proteins inter­ act with DNA and with each other to the achievement of replication and to the maintenance of the physiological structure of the chromo­ somes is the subject of the contributions collected in this volume. The presentations and discussions during this workshop reinforced the view that DNA replication in vivo can only be achieved through the cooperation of a high number of enzymes, proteins and other cofactors.