Methods in enzymology 485 - Constitutive Activity in Receptors and Other Proteins, Part 2. Melvin I. Simon. Download (pdf, 2. 9 Mb) Donate Read.
Constitutive activity and inverse agonism at the α1a and α1b adrenergic receptor subtypes. Measurement of inverse agonism of the cannabinoid receptor. This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. It is extensively referenced, with useful figures and tables throughout the volume. Expert authors who are leaders in the field. Extensively referenced and useful figures and tables. Provides hints and tricks to facilitate reproduction of methods. Affiliations and Expertise. The Salk Institute, La Jolla, CA, USA.
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This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. A. B. C. 9780123812995, 0123812992. Constitutive Activity.
Constitutive Activity in Receptors and Other Proteins, Part B. Tung M. Fong, in Methods in Enzymology, 2010. The cannabinoid receptors are G protein-coupled receptors that are activated by endocannabinoids or exogenous agonists such as. Several methods have been used to measure inverse agonist activity of ligands for the cannabinoid receptors, including Gi-cAMP second messenger assay, GTPγS binding assay, and assays. Each assay has its advantages and limitations, and the Gi-cAMP second messenger assay appears to provide the best overall measurement of inverse agonism in a cellular environment. Therapeutic Areas I: Central Nervous System, Pain, Metabolic Syndrome, Urology, Gastrointestinal and Cardiovascular.
Constitutive Activity in Receptors and Other Proteins, Part B · Methods in Enzymology. Medical Science Nonfiction.
In: Constitutive activity in receptors and other proteins. Part A. Methods in Enzymology. Elsevier, Amsterdam, pp. 397-412. In this chapter, we summarize methods used for assessing the constitutive activity of Cpr2 and its mutants, which could be beneficial for other GPCR studies. Item Type: Book Section.
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Amyloid, Prions, and Other Protein Aggregates, Part C: Volume 413 (Methods in Enzymology).