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ISBN:0122405455
Author: Henry F. Epstein,Diane C. Shakes,Leslie Wilson,Paul T. Matsudaira
ISBN13: 978-0122405457
Title: Caenorhabditis elegans, Volume 48: Modern Biological Analysis of an Organism (Methods in Cell Biology)
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ePUB size: 1427 kb
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Language: English
Category: Medicine and Health Sciences
Publisher: Academic Press (October 9, 1995)
Pages: 659

Caenorhabditis elegans, Volume 48: Modern Biological Analysis of an Organism (Methods in Cell Biology) by Henry F. Epstein,Diane C. Shakes,Leslie Wilson,Paul T. Matsudaira



Methods in Cell Biology VOLUME 48 Cuenavhubditis eleguns: Modern Biological Analysis of an Organism. Methods in Cell Biology Prepared under the Auspices of the American Society for Cell Biology. VOLUME 48 Cuenorhubditis elegans: Modern Biologcal Analysis of an Organism.

eBook ISBN: 9780080859460. Imprint: Academic Press. Published Date: 20th September 1995. Page Count: 659. View all volumes in this series: Methods in Cell Biology. Because C. elegans is a simple and malleable organism with a small genome and few cell types, it provides an elegant demonstration of functions fundamental to multicellular organisms.

Caenorhabditis elegans, Volume 48 Modern Biological Analysis of an Organism Methods in Cell Biology.

Henry F. Epstein, Diane C. Shakes.

Because C.

Geldziler B, Marcello MR, Shakes DC, and Singson A. (2011) The Genetics and Cell Biology of Fertilization. Shakes DC. (2011) For male Caenorhabditis elegans, sperm activation is a just-in-time event. 2011) PLoS Genetics 7(11): e1002392. Caenorhabditis elegans: Modern biological analysis of an organism. Methods in Cell Biology Volume 48. Academic Press.

Cell Death provides a current and comprehensive collection of methods for the study of cell death. Using a diverse range of technical approaches and model systems, the chapters in this volume cover topics fromthe cellular and organismal to the molecular and anatomical.

Caenorhabditis elegans (C. elegans) is recognized as a powerful model organism for screening potential drug compounds and validating drug efficiency prior to more costly and time consuming in vivo studies (Artal-Sanz et al. 2006). C. elegans offers a variety of advantages in the drug development process. In addition, C. elegans studies are cost effective. Epstein HF, Shakes DC (1995) Methods in cell biology, Caenorhabditis elegans: modern biological analysis of an organism, vol. 48. Academic, New YorkGoogle Scholar. Fantz DA, Jacobs D, Glossip D, Kornfeld K (2001) Docking sites on substrate proteins direct extracellular signal-regulated kinase to phosphorylate specific residues.

The first of its kind, this laboratory handbook emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. Four primary sections--Genetic and Culture Methods, Neurobiology, Cell and Molecular Biology, and Genomics and Informatics--cross disciplines in this volume's integrated approach to C. elegans. Because C. elegans is a simple and malleable organism with a small genome and few cell types, it provides an elegant demonstration of functions fundamental to multicellular organisms. The discipline has expanded manyfold as researchers continue to find this small soil nematode to be the model of choice for studying specific pathways, stages of development, and cell types. By directing its audience not just to tried-and-true recipes for research, but also to databases and other innovative sources of information, this comprehensive collection is intended to guide investigators of C. elegans for years to come. Key Features* First single-source book detailing explanations of current and classic C. elegans methodologies* Diversity and scope of techniques covered expected to be useful to the broadening community of C. elegans researchers for years to come* Techniques range from reverse genetics and mutagenesis, to laser ablation and electrophysiology, to in situ hybridization and DNA sequencing methods* Appendices include resource information important to the C. elegans community, including the C. elegans Genetics Center and Internet resources like the Worm Community System and AceDB* Illustrated with more than 100 tables and figures