|Title:||Vertebrate Sex Determination (Cytogenetic & Genome Research)|
|Format:||lrf txt docx azw|
|ePUB size:||1867 kb|
|FB2 size:||1812 kb|
|DJVU size:||1928 kb|
|Category:||Medicine and Health Sciences|
|Publisher:||S. Karger; 1 edition (December 22, 2003)|
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Conference: 21st International Chromosome Conference (ICC), Volume: 148. Cite this publication. Sex chromosomes are the most dynamic entity in any genome having unique morphology, gene content, and evolution. They have evolved multiple times and independently throughout vertebrate evolution. One of the major genomic changes that pertain to sex chromosomes involves the amplification of common repeats
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Sex-determining mechanisms (SDMs) set an individual's sexual fate by its genotype (genotypic sex determination, GSD) or environmental factors like temperature (temperature- dependent sex determination, TSD), as in turtles where the GSD "trigger" remains unknown. SDMs co-evolve with turtle chromosome number, perhaps because fusions/fissions alter the relative position/regulation of sexual development genes.
Both male and female heterogametic sex-determination systems have been characterized, as well as epistatic and environmental influences on sex determination. Genome Res. Publication Date: 2013 Oct. Date Detail
Investigating the evolutionary processes influencing the origin, evolution, and turnover of vertebrate sex chromosomes requires the classification of sex chromosome systems in a great diversity of species. Among amniotes, squamates (lizards and snakes) - and gecko lizards in particular - are worthy of additional study. Geckos possess all major vertebrate sex-determining systems, as well as multiple transitions among them, yet we still lack data on the sex-determining systems for the vast majority of species.
Mosaic Trisomy 12 Associated with Overgrowth Detected in Fibroblast Cell Lines Mosaic trisomy 12 is a rare anomaly, and only 9 cases of live births with this condition have been reported in the literature. Chromosomal Rearrangements during Turtle Evolution Altered the Synteny of Genes Involved in Vertebrate Sex Determination Sex-determining mechanisms (SDMs) set an individual's sexual fate by its genotype (genotypic sex determination, GSD) or environmental factors like temperature (temperature- dependent sex determination, TSD), as in turtles where the GSD trigger remains unknown.
Sex determination system in birds is characterized by a homo-(Neognatae) and heteromorphic (Paleognatae) sex chromosomes. Heterogametic sex is female (ZZ/ZW system). DMRT1 gene is a gene regarded as a main male sex determining factor in this group of animals. Complete sex inversion is not typical for species with genotypic sex determination (GSD), although the effect of estrogen metabolites is noted for birds. For birds epigenetic mechanisms of regulation (methylation of DNA and non-coding RNA) have been described for sex controlling genes such as CYP19A1 and DMRT1. 2013) The Molecular Genetics of Avian Sex Determination and Its Manipulation. Genesis, 51, 325-336.
Sex chromosomes are the most dynamic entity in any genome having unique morphology, gene content, and evolution. One of the major genomic changes that pertain to sex chromosomes involves the amplification of common repeats.
Flowering plants were one of the earliest classes of organisms in which sex-determining mechanisms were investigated and found, and the red and white campions, Silene dioica and S. alba, proved particularly favorable.